NTP Diversity Enhancement Seminar by Eduardo Candelario-Jalil

Prostagladin E2 Regulation of blood-brain barrier permeability after ischemic stroke

Date
Thursday, April 27, 2017
Time
4 p.m.
Location
John D. Wiley Conference Center, Waisman Center
Description
Cyclooxygenase-2 (COX-2) significantly contributes to the neuroinflammatory response to ischemic brain injury. Increased COX-2 activity leads to overproduction of prostaglandin E2 (PGE2), which alters the permeability of the blood-brain barrier (BBB) after ischemia. In this talk, we present new evidence of the role of different PGE2 receptors in BBB opening following ischemic stroke
Contact
262-4932, tholtz@wisc.edu