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Covid-19 Notice

All campus events (including Division of Extension sponsored events outside of Dane County) are canceled through June 30, with limited exceptions to be granted by deans or vice chancellors. Even if an event is not yet labeled as canceled, it's likely to be canceled, postponed or modified to online only, from now through June 30. Please check with organizers before attending.

Neuroscience & Public Policy Seminar by Dr. Lauren Schmitz

"Examining Sex Differences in Pleiotropic Effects for Depression and Smoking Using Polygenic and Gene-Region Aggregation Techniques"

Event Details

Thursday, November 14, 2019
3-4 p.m.
Biotechnology Auditorium Room 1111 (425 Henry Mall), Genetics-Biotechnology Center Building
Sex differences in rates of depression are thought to contribute to sex differences in smoking behavior. Despite evidence of biological ties, research has not examined whether genetic factors that contribute to depression-smoking comorbidity differ by sex. We utilized two statistical aggregation techniques—polygenic scores (PGSs) and sequence kernel association testing (SKAT)—to assess the degree of pleiotropy between these behaviors and moderation by sex in the Health and Retirement Study.