Humans as a model for animals: Patterning preclinical reproducibility reform after clinical research

This talk asks why two industry publications triggered what today has become known as the “reproducibility crisis” in biomedicine. Nelson argues that the reason these publications had such an impact on science policy makers is that they took a widely recognized problem—the problem of ‘translating’ basic science discoveries into clinical applications—and reframed it as a problem with the quality of the science rather than a problem of moving the science from bench to bedside.