Physical Chemistry Seminar

Ron Elber, The University of Texas at Austin. Myosin II is a molecular machine that converts chemical to mechanical energy and enables muscle operations. After a power stroke, which is a step of obvious functional importance, a recovery transition completes the cycle and returns the molecular machine to its pre-stroke state. Atomically detailed simulations in the framework of the Milestoning theory are used to calculate kinetics and mechanisms of the recovery stroke.