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Methods to Evaluate and Perturb the Activity of the Human Proteasome with Small Molecules

Pharmaceutical Sciences Seminar with Dr. Darci Trader, Purdue University

Event Details

Date
Friday, November 6, 2020
Time
10-11 a.m.
Location
Description
The degradation of proteins is an essential cellular process. The proteasome, a multi-catalytic enzyme, is mainly responsible for degrading proteins that are no longer required by the cell. My lab has focused on the development of activity probes that can monitor real-time proteasome activity biochemically and in live cells. These probes can be applied in variety of analytical methods including confocal microscopy, flow cytometry, and fluorescent plate readers.
Cost
Free

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