BMI Seminar: Zijian Ni, PhD Thesis Defense
Statistical Methods for Improving Data Quality in Modern RNA Sequencing Experiments
Event Details
Date
Friday, May 6, 2022
Time
10-11 a.m.
Location
Description
Graduate student Zijian Ni will present SpotClean, a probabilistic model to adjust for spot swapping, an artifact of bleeding between the spot-specific barcodes that bind mRNA in recent spatial transcriptomics experiments. SpotClean increases the power and precision of downstream analyses with highlights in improved cancer marker signals, tumor/normal delineation, and tissue annotation in cancer studies.
Cost
Free
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