WID-DOW Seminar
Meike Wortel, University of Amsterdam
Event Details
Date
Tuesday, March 18, 2014
Time
4-5 p.m.
Description
Metabolic States with Maximal Specific Rate Carry Flux through an Elementary Flux Mode.
Cellular growth rates are important maximization targets in biotechnology. We characterize maximal-specific-rate states of metabolic networks with arbitrary size & complexity. Optimal states are elementary flux modes which are minimal metabolic networks, operating at a thermodynamically-feasible steady state with one independent flux. Result may help optimize genome-scale kinetic models.
Cellular growth rates are important maximization targets in biotechnology. We characterize maximal-specific-rate states of metabolic networks with arbitrary size & complexity. Optimal states are elementary flux modes which are minimal metabolic networks, operating at a thermodynamically-feasible steady state with one independent flux. Result may help optimize genome-scale kinetic models.
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Cost
Free and open to campus. Contact Herman Stampfli for building access.
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