Biostatistics and Medical Informatics Department Seminar with Wenyi Wang (University of Texas MD Anderson Cancer Center)

Intra-tumor heterogeneity is characterized by a diverse population of tumor clones and subclones which are important drivers of tumor evolution and therapeutic response. However, accurate subclonal reconstruction at scale remains challenging. Professor Wang will describe a machine learning algorithm (CLiPP) developed by her lab that highlights sMF as a key feature of cancer evolution.